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Merzel, Rachel

Education

B. A. 2012

Wesleyan University

    About This Team Member

    Rachel Merzel (Wallace) graduated with a B.A. in Chemistry from Wesleyan University in 2012. At Wesleyan she worked with Prof. Albert J. Fry on mechanistic studies involving the electrochemical oxidation of diphenylacetaldehyde. In the fall of 2013, Rachel began graduate school in the University of Michigan's Chemistry Department in the Inorganic cluster. She joined the Banaszak Holl group in May 2014, where her research focuses on designing targeted drug delivery using polymer-drug conjugates and the functionalization of silicon nanoparticles for imaging applications.  Rachel was awarded an NSF Graduate Fellowship in 2014.

    She was awarded the Florence Fenwick outstanding graduate student instructor award in 2017.

    Rachel's work on nanoplastics in the environment was featured in congressional testimony in 2017 (starts around 1 h 33 min mark in attached link).

     

    Publications

    Folate binding protein: Therapeutic natural nanotechnology for folic acid, methotrexate, and leucovorin

    R.L. Merzel, S.M. Boutom, J. Chen, C. Frey, K. Shedden, E. N. G. Marsh, M. M. Banaszak Holl
    Nanoscale
    2017
    9
    2603-2615

    Substrate-Triggered Exosite Binding: Synergistic Dendrimer/Folic Acid Action for Achieving Specific, Tight-Binding to Folate Binding Protein

    J. Chen, M. A. van Dongen, R. L. Merzel, C. A. Dougherty, A. K. Kandulura, P. S. Low, E. N G. Marsh, M. M. Banaszak Holl
    Biomacromolecules
    2016
    17
    922-927

    Folate binding protein-Outlook for drug delivery applications

    R. L. Merzel, J.-J. Chen, E. N. G. Marsh, M. M. Banaszak Holl
    Chinese Chemical Letters
    2015
    26
    426-430

    Quantitative Measurement of Cationic Polymer Vector and Polymer-pDNA Polyplex Intercalation into the Cell Plasma Membrane

    S. Vaidyanathan, K. B. Anderson, R. L. Merzel, B. Jacobovitz, M. P. Kaushik, C. N. Kelly, M. A. van Dongen, C. A. Dougherty, B. G. Orr, and M. M. Banaszak Holl
    ACS Nano
    2015
    9
    6097-6109