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Silpe, Justin

Education

Bachelor of Arts

University of Michigan, 2012

Masters of Science

University of Michigan, 2013

    About This Team Member

    Justin Silpe started as a  third year undergraduate pursuing an individual concentration program in “Theoretical Medicine & Bioethics”. He began his work under Dr. Seok Ki Choi at the Michigan Nanotechnology Institute for Medicine and Biological Sciences studying the release kinetics of a photolabile linker exposed to varying wavelengths and pH environments.  Justin continued to work with Dr. Choi  and the Banaszak Holl lab on SPR binding studies of precisely defined folate and methotrexate ligands as part of his research for the Master's degree in Macromolecular Science and Engineering.

    Publications

    Avidity Mechanism of Dendrimer-Folic Acid Conjugates

    MA van Dongen, JE Silpe, CA Dougherty, AK Kanduluru, SK Choi, BG, Orr, PS Low, MM Banaszak Holl
    Molecular Pharmaceutics
    2014
    11
    1696-1706

    Poly(amidoamine) Dendrimer-Methotrexate Conjugates: The Mechanism of Interaction with Folate Binding Protein

    M. A. van Dongen, R. Rattan, J. Silpe, C. Dougherty, N. L. Michmerhuizen, M. Van Winkle, B. Huang, S.-K. Choi, K. Sinniah, B.G. Orr, M. M. Banaszak Holl
    Molecular Pharmaceutics
    2014
    11
    4049-4058

    Avidity Modulation of Folated-Targeted Multivalent Dendrimers for Evaluating Biophysical Models of Cancer Targeting Nanoparticles

    J. E. Silpe, M. Sumit, T. P. Thomas, B. Huang, A. Kotlyar, M. A. van Dongen, M. M. Banaszak Holl, B. G. Orr, S. K. Choi
    ACS Chemical Biology
    2013
    8
    2063-2071

    Dendrimer-Based Multivalent Vancomycin Nanoplatform for Targeting the Drug-Resistant Bacterial Surface

    S.K Choi, A. Myc, J.E. Silpe, M. Sumit, P.T. Wong, K. McCarthy, A.M. Desai, T.P. Thomas, A. Kotlyar, M. M. Banaszak Holl, B. G. Orr, J.R. Baker
    ACS Nano
    2013
    7
    214-228