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Chen, Junjie

Education

Bachelors of Science

2013 Nanjing University

    About This Team Member

    Junjie (JJ) received a B.S. in chemistry from Nanjing University, China in June 2013. In NJU, he was involved in bio-analytical and fluorescent probe development projects. He came to Michigan chemistry department as a chembio graduate student in the summer of 2013 and joined Banaszak Holl's lab in May 2014. JJ's initial project focused on the interaction of folate binding protein with folic acid, folic acid conjugates, and antifolates. He is currently part of a team translating the results to an in vivo drug delivery study.  He is also studying the structure of the anterior cruciate ligament and mechanisms of ligament failure.

    Besides science, he also loves classical music, history and travelling

     

    Publications

    Conjugation Dependent Interaction of Folic Acid with Folate Binding Protein

    RL Merzel, C Frey, J Chen, R. Garn, M. van Dongen, CA Dougherty, A Kumar Kandaluru, PS Low, ENG Marsh, MM Banaszak Holl
    Bioconjugate Chemistry
    2017
    28
    2350-2360

    Dendrimer and dendrimer-conjugate protein complexes and protein coronas

    J. Chen, M. M. Banaszak Holl
    Canadian Journal of Chemistry
    2017
    95
    903-906

    Folate binding protein: Therapeutic natural nanotechnology for folic acid, methotrexate, and leucovorin

    R.L. Merzel, S.M. Boutom, J. Chen, C. Frey, K. Shedden, E. N. G. Marsh, M. M. Banaszak Holl
    Nanoscale
    2017
    9
    2603-2615

    Folate-Binding Protein Self-Aggregation Drives Agglomeration of Folic Acid Targeted Iron Oxide Nanoparticles

    J. Chen, S. Klem, A. K. Jones, B. G. Orr, M. M. Banaszak Holl
    Bioconjugate Chemistry
    2017
    28
    81-87

    Cationic Polymer Intercalation into the Lipid Membrane Enables Intact Polyplex DNA Escape from Endosomes for Gene Delivery

    S. Vaidyanathan, J. Chen, B. G. Orr, M. M. Banaszak Holl
    Molecular Pharmaceutics
    2016
    13
    1967-1978

    Substrate-Triggered Exosite Binding: Synergistic Dendrimer/Folic Acid Action for Achieving Specific, Tight-Binding to Folate Binding Protein

    J. Chen, M. A. van Dongen, R. L. Merzel, C. A. Dougherty, A. K. Kandulura, P. S. Low, E. N G. Marsh, M. M. Banaszak Holl
    Biomacromolecules
    2016
    17
    922-927

    Folate binding protein-Outlook for drug delivery applications

    R. L. Merzel, J.-J. Chen, E. N. G. Marsh, M. M. Banaszak Holl
    Chinese Chemical Letters
    2015
    26
    426-430