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Dougherty, Casey

Education

Bachelor of Science

University of Pittsburgh, 2010

Doctor of Philosophy

University of Michigan, 2015

    About This Team Member

    Casey received a B.S. in Chemistry and minor in Mathematics from the University of Pittsburgh in May 2010. At Pittsburgh, she was involved in genetics, bio-analytical, and polymer coating research projects. She entered Michigan's chemistry graduate program in the fall of 2010 to study Materials-Organic Chemistry. Casey joined the Banaszak Holl group in 2011, and her work focuses on the synthesis and characterization of fluorescent dendrimers and their applications.

    Casey won the chemistry department's 2013 American Chemical Society outstanding graduate student award for research and teaching.

    She was a post-doctoral associate in the group of Hao Hong in the University of Michigan radiology department and in the group of Neil Marsh at UM chemistry.

     

    Casey is now an assistant professor at Iona College.

     

     

    Graduation Day!

     

     

    Publications

    Increase in Dye:Dendrimer Ratio Decreases Cellular Uptake of Neutral Dendrimers in RAW Cells

    S. Vaidyanathan, M. Kaushik, C. Dougherty, R. Rattan, S. N. Goonewardena, M. M. Banaszak Holl, J. Monano, S. DiMaggio
    ACS Biomaterials Science & Engineering
    2016
    2
    1540-1545

    Rapid Exchange Between Free and Bound States in RNA-Dendrimer Polyplexes: Implications on the Mechanism of Delivery and Release

    A. Shakya; C. A. Dougherty; Y. Xue; H. Al-Hashimi; M. M. Banaszak Holl
    Biomacromolecules
    2016
    17
    154-164

    Substrate-Triggered Exosite Binding: Synergistic Dendrimer/Folic Acid Action for Achieving Specific, Tight-Binding to Folate Binding Protein

    J. Chen, M. A. van Dongen, R. L. Merzel, C. A. Dougherty, A. K. Kandulura, P. S. Low, E. N G. Marsh, M. M. Banaszak Holl
    Biomacromolecules
    2016
    17
    922-927

    Fluorophore:Dendrimer Ratio Impacts Cellular Uptake and Intracellular Fluorescence Lifetime

    C. A. Dougherty, S. Vaidyanathan, B. G. Orr, M. M. Banaszak Holl
    Bioconjugate Chemistry
    2015
    26
    304-315

    Generation 3 PAMAM Dendrimer TAMRA Conjugates Containing Precise Dye/Dendrimer Ratios

    J. Manono, C. A. Dougherty, K. Jones, J. DeMuth, M. M. Banaszak Holl, S. DiMaggio
    Materials Today Communications
    2015
    4
    86-92

    Quantitative Measurement of Cationic Polymer Vector and Polymer-pDNA Polyplex Intercalation into the Cell Plasma Membrane

    S. Vaidyanathan, K. B. Anderson, R. L. Merzel, B. Jacobovitz, M. P. Kaushik, C. N. Kelly, M. A. van Dongen, C. A. Dougherty, B. G. Orr, and M. M. Banaszak Holl
    ACS Nano
    2015
    9
    6097-6109

    Avidity Mechanism of Dendrimer-Folic Acid Conjugates

    MA van Dongen, JE Silpe, CA Dougherty, AK Kanduluru, SK Choi, BG, Orr, PS Low, MM Banaszak Holl
    Molecular Pharmaceutics
    2014
    11
    1696-1706

    Isolation and Characterization of Precise Dye/Dendrimer Ratios

    C. A. Dougherty, J. C. Furgal, M. A. van Dongen, T. Goodson, M. M. Banaszak Holl, J. Manono, S. DiMaggio
    Chemistry a European Journal
    2014
    20
    4638-4645

    Multivalent Polymers for Drug Delivery and Imaging: The Challenges of Conjugation

    M. A. van Dongen, C. A. Dougherty, M. M. Banaszak Holl
    Biomacromolecules
    2014
    15
    3215-3234

    Poly(amidoamine) Dendrimer-Methotrexate Conjugates: The Mechanism of Interaction with Folate Binding Protein

    M. A. van Dongen, R. Rattan, J. Silpe, C. Dougherty, N. L. Michmerhuizen, M. Van Winkle, B. Huang, S.-K. Choi, K. Sinniah, B.G. Orr, M. M. Banaszak Holl
    Molecular Pharmaceutics
    2014
    11
    4049-4058