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Folate binding protein: Therapeutic natural nanotechnology for folic acid, methotrexate, and leucovorin

Folate binding protein: Therapeutic natural nanotechnology for folic acid, methotrexate, and leucovorin

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R.L. Merzel, S.M. Boutom, J. Chen, C. Frey, K. Shedden, E. N. G. Marsh, M. M. Banaszak Holl.
Nanoscale
2017,
9,
2603-2615.

Folate-Binding Protein Self-Aggregation Drives Agglomeration of Folic Acid Targeted Iron Oxide Nanoparticles

Folate-Binding Protein Self-Aggregation Drives Agglomeration of Folic Acid Targeted Iron Oxide Nanoparticles

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J. Chen, S. Klem, A. K. Jones, B. G. Orr, M. M. Banaszak Holl.
Bioconjugate Chemistry
2017,
28,
81-87.

Increase in Dye:Dendrimer Ratio Decreases Cellular Uptake of Neutral Dendrimers in RAW Cells

Increase in Dye:Dendrimer Ratio Decreases Cellular Uptake of Neutral Dendrimers in RAW Cells

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S. Vaidyanathan, M. Kaushik, C. Dougherty, R. Rattan, S. N. Goonewardena, M. M. Banaszak Holl, J. Monano, S. DiMaggio.
ACS Biomaterials Science & Engineering
2016,
2,
1540-1545.

Role of Cell Membrane-Vector Interactions in Successful Gene Delivery

Role of Cell Membrane-Vector Interactions in Successful Gene Delivery

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S. Vaidyanathan, B. G. Orr, M. M. Banaszak Holl .
Accounts of Chemical Research
2016,
49,
1486-1493.

In vivo targeting of metastatic breast cancer via tumor vasculature-specific nano-graphene oxide

In vivo targeting of metastatic breast cancer via tumor vasculature-specific nano-graphene oxide

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D. Yang, L. Feng, C. A. Dougherty, K. E. Luker, D. Chen. M. A. Cauble, M. M. Banaszak Holl, G. D. Luker, B. D. Ross, Z. Liu, H. Hong.
Biomaterials
2016,
104,
361-371.

Cationic Polymer Intercalation into the Lipid Membrane Enables Intact Polyplex DNA Escape from Endosomes for Gene Delivery

Cationic Polymer Intercalation into the Lipid Membrane Enables Intact Polyplex DNA Escape from Endosomes for Gene Delivery

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S. Vaidyanathan, J. Chen, B. G. Orr, M. M. Banaszak Holl.
Molecular Pharmaceutics
2016,
13,
1967-1978.

Substrate-Triggered Exosite Binding:

Substrate-Triggered Exosite Binding: Synergistic Dendrimer/Folic Acid Action for Achieving Specific, Tight-Binding to Folate Binding Protein

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J. Chen, M. A. van Dongen, R. L. Merzel, C. A. Dougherty, A. K. Kandulura, P. S. Low, E. N G. Marsh, M. M. Banaszak Holl.
Biomacromolecules
2016,
17,
922-927.

Rapid Exchange Between Free and Bound States in RNA?Dendrimer Polyplexes: Implications on the Mechanism of Delivery and Release

Rapid Exchange Between Free and Bound States in RNA-Dendrimer Polyplexes: Implications on the Mechanism of Delivery and Release

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A. Shakya; C. A. Dougherty; Y. Xue; H. Al-Hashimi; M. M. Banaszak Holl.
Biomacromolecules
2016,
17,
154-164.

G5 PAMAM dendrimer versus liposome: A comparison study on the in vitro transepithelial transport and in vivo oral absorption of

G5 PAMAM dendrimer versus liposome: A comparison study on the in vitro transepithelial transport and in vivo oral absorption of simvastatin

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Q. Rong, H. R. Zhang, L. Xu, W.W. Shen, C. Chen, C. Wang, Y. N. Cao, Y. A. Wang, M. A. van Dongen, B. He, S. L. Wang, G. Liu, M. M. Banaszak Holl, Q. Zhang.
Nanomedicine - Nanotechnology, Biology, and Medicine
2015,
11,
1141-1151.

Characterization of Folic Acid and Poly(amidoamine) Dendrimer Interactions with Folate Binding Protein: A Force-Pulling Study

Characterization of Folic Acid and Poly(amidoamine) Dendrimer Interactions with Folate Binding Protein: A Force-Pulling Study

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P.R. Leroueil, S. DiMaggio, A. N. Leistra, C. D. Blanchette, C. Orme, K. Sinniah, B. G. Orr, and M. M. Banaszak Holl.
Journal of Physical Chemistry B
2015,
119,
11506-11512.

High-resolution NMR characterization of low abundance oligomers of amyloid

High-resolution NMR characterization of low abundance oligomers of amyloid-beta without purification

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S. Kotler, J. Brender, S. Vivekanandan, Y. Suzuki, K. Yamamoto, M. Monette, J. Krishnamoorthy, P. Walsh, M. Cauble, M. M. Banaszak Holl, E. N. G. Marsh, A. Ramamoorthy.
Scientific Reports
2015,
5,
11811.

G5-PEG PAMAM dendrimer incorporating nanostructured lipid carriers enhance oral bioavailability and plasma lipid-lowering effect

G5-PEG PAMAM dendrimer incorporating nanostructured lipid carriers enhance oral bioavailability and plasma lipid-lowering effect of probucol

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R. Qi, Y. Z. Li, C. Chen, Y. N. Cao, M. M. Yu, L. Xu, B. He, X. Jie, W. W. Shen, Y. N. Wang, M. A. van Dongen, G. Q. Lui, M. M. Banaszak Holl, Q. Zhang, X. Ke.
Journal of Controlled Release
2015,
210,
160-168.

Generation 3 PAMAM Dendrimer TAMRA Conjugates Containing Precise Dye/Dendrimer Ratios

Generation 3 PAMAM Dendrimer TAMRA Conjugates Containing Precise Dye/Dendrimer Ratios

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J. Manono, C. A. Dougherty, K. Jones, J. DeMuth, M. M. Banaszak Holl, S. DiMaggio.
Materials Today Communications
2015,
4,
86-92.

Quantitative Measurement of Cationic Polymer Vector and Polymer–pDNA Polyplex Intercalation into the Cell Plasma Membrane

Quantitative Measurement of Cationic Polymer Vector and Polymer-pDNA Polyplex Intercalation into the Cell Plasma Membrane

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S. Vaidyanathan, K. B. Anderson, R. L. Merzel, B. Jacobovitz, M. P. Kaushik, C. N. Kelly, M. A. van Dongen, C. A. Dougherty, B. G. Orr, and M. M. Banaszak Holl.
ACS Nano
2015,
9,
6097-6109.

Force Spectroscopy of Multivalent Binding of Riboflavin-Conjugated Dendrimers to Riboflavin Binding Protein

Force Spectroscopy of Multivalent Binding of Riboflavin-Conjugated Dendrimers to Riboflavin Binding Protein

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A Leistra, J. Han, S. Tang, B. G. Orr, M. M. Banaszak Holl, S. K. Choi, K. Sinniah.
Journal of Physical Chemistry B
2015,
119,
5785-5792.
See:

Folate binding protein—Outlook for drug delivery applications

Folate binding protein-Outlook for drug delivery applications

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R. L. Merzel, J.-J. Chen, E. N. G. Marsh, M. M. Banaszak Holl.
Chinese Chemical Letters
2015,
26,
426-430.

Oral Absorption Enhancement of Probucol by PEGylated G5 PAMAM Dendrimer Modified Nanoliposomes

Oral Absorption Enhancement of Probucol by PEGylated G5 PAMAM Dendrimer Modified Nanoliposomes

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Q. Ma, Y.C. Han, C. Chen, Y. N. Cao, S. L. Wang, W. W. Shen, H. Y. Zhang, Y. Z. Li, M. A. van Dongen, B. He, M. M. Yu, L. Xu, M. M. Banaszak Holl, G. Liu, Q. Zhang, R. Qi.
Molecular Pharmaceutics
2015,
12,
665-674.

Fluorophore:Dendrimer Ratio Impacts Cellular Uptake and Intracellular Fluorescence Lifetime

Fluorophore:Dendrimer Ratio Impacts Cellular Uptake and Intracellular Fluorescence Lifetime

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C. A. Dougherty, S. Vaidyanathan, B. G. Orr, M. M. Banaszak Holl.
Bioconjugate Chemistry
2015,
26,
304-315.

The role of caveolin-1 and syndecan-4 in the internalization of PEGylated PAMAM dendrimer polyplexes into myoblast and hepatic c

The role of caveolin-1 and syndecan-4 in the internalization of PEGylated PAMAM dendrimer polyplexes into myoblast and hepatic cells

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W.W. Shen, M. A. van Dongen, Y.C. Han, M. M. Yu, Y. Z. Li, G. Liu, M. M. Banaszak Holl, R. Qi.
European Journal of Pharmaceutics and Biopharmaceutics
2014,
88,
658-663.

Poly(amidoamine) Dendrimer–Methotrexate Conjugates: The Mechanism of Interaction with Folate Binding Protein

Poly(amidoamine) Dendrimer-Methotrexate Conjugates: The Mechanism of Interaction with Folate Binding Protein

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M. A. van Dongen, R. Rattan, J. Silpe, C. Dougherty, N. L. Michmerhuizen, M. Van Winkle, B. Huang, S.-K. Choi, K. Sinniah, B.G. Orr, M. M. Banaszak Holl.
Molecular Pharmaceutics
2014,
11,
4049-4058.