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Drug and Gene Delivery

Polyplex Exposure Inhibits Cell Cycle, Increases Inflammatory Response, and Can Cause Protein Expression without Cell Division

Submitted by bhgroup_admin on Mon, 04/15/2013 - 09:01.

Polyplex Exposure Inhibits Cell Cycle, Increases Inflammatory Response, and Can Cause Protein Expression without Cell Division

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R. L. Matz, B Erickson, S. Vaidyanathan, J. F. Kukowska-Latallo, J. R. Baker, B. G. Orr, and M. M. Banaszak Holl.
Molecular Pharmaceutics
2013,
10,
1306-1317.
See:
Erickson, Blake
Matz, Becky
Vaidyanathan, Sriram

Attractive Hydration Forces in DNA-Dendrimer Interactions on the Nanometer Scale

Submitted by bhgroup_admin on Thu, 03/07/2013 - 13:05.

Attractive Hydration Forces in DNA-Dendrimer Interactions on the Nanometer Scale

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M. Mills, B. G. Orr, M. M. Banaszak Holl, I. Andricioaei.
Journal of Physical Chemistry B
2013,
117,
973-981.
See:

Dendrimer-Based Multivalent Vancomycin Nanoplatform for Targeting the Drug-Resistant Bacterial Surface

Submitted by bhgroup_admin on Fri, 02/08/2013 - 06:35.

Dendrimer-Based Multivalent Vancomycin Nanoplatform for Targeting the Drug-Resistant Bacterial Surface

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S.K Choi, A. Myc, J.E. Silpe, M. Sumit, P.T. Wong, K. McCarthy, A.M. Desai, T.P. Thomas, A. Kotlyar, M. M. Banaszak Holl, B. G. Orr, J.R. Baker.
ACS Nano
2013,
7,
214-228.
See:
Choi, Seok-ki
Silpe, Justin

Intrinsic Dynamics of DNA-Polymer Complexes: A Mechanism for DNA Release

Submitted by bhgroup_admin on Fri, 09/07/2012 - 18:53.

Intrinsic Dynamics of DNA-Polymer Complexes: A Mechanism for DNA Release

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L. E. Prevette, E. N. Nikolova, H. M. Al-Hashimi, M. M. Banaszak Holl.
Molecular Pharmaceutics
2012,
9,
2743-2749.
See:
Prevette, Lisa

Efficient in vitro siRNA delivery and Intramuscular Gene Silencing using PEG-Modified PAMAM Dendrimers

Submitted by bhgroup_admin on Thu, 06/28/2012 - 12:41.

Efficient in vitro siRNA delivery and Intramuscular Gene Silencing using PEG-Modified PAMAM Dendrimers

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Y. Tang, Y.-B. Li, B. Wang, R.-Y. Lin, M. van Dongen, D. M. Zurcher, X.-Y. Gu, M. M. Banaszak Holl, G. Liu, R. Qi.
Molecular Pharmaceutics
2012,
9,
1812-1821.
See:
Rong Qi
van Dongen, Mallory

Best Practices for Purification and Characterization of PAMAM Dendrimer

Submitted by bhgroup_admin on Thu, 06/21/2012 - 14:56.

Best Practices for Purification and Characterization of PAMAM Dendrimer

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D. G. Mullen, A. Desai, M. A. Van Dongen, M. Barash, J. R. Baker, M. M. Banaszak Holl.
Macromolecules
2012,
45,
5316-5320.
See:
Barash, Mark
Mullen, Douglas
van Dongen, Mallory

Dual-wavelength digital holographic imaging with phase background subtraction

Submitted by bhgroup_admin on Wed, 06/13/2012 - 11:11.

Dual-wavelength digital holographic imaging with phase background subtraction

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A. Khmaladze, R. Matz, J. Jasensky, E. Seeley, M. M. Banaszak Holl, Z. Chen.
Optical Engineering
2012,
51,
055801.
See:
Matz, Becky

Cell Volume Changes During Apoptosis Monitored in Real Time Using Digital Holographic Microscopy

Submitted by bhgroup_admin on Wed, 06/13/2012 - 11:06.

Cell Volume Changes During Apoptosis Monitored in Real Time Using Digital Holographic Microscopy

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A. Khmaladze, R. Matz, T. Epstein, J. Jasensky, M. M. Banaszak Holl, Z. Chen.
Journal of Structural Biology
2012,
178,
270-278.
See:
Matz, Becky

Dendrimer-Based Nanoparticle Therapies: Can Uniform Multifunctional Therapeutics Be Made with Current Chemical Approaches?

Submitted by bhgroup_admin on Tue, 06/05/2012 - 19:57.

in Multifunctional Nanoparticles for Drug Delivery Applications: Imaging, Targeting and Delivery; Book Series: Nanostructure Science and Technology Pages: 295-313 (2012).

See:
McNerny, Dan
Mullen, Douglas

Bifunctional PAMAM Dendrimer Conjugates of Folic Acid and Methotrexate with Defined Ratio

Submitted by bhgroup_admin on Thu, 05/10/2012 - 00:48.

Bifunctional PAMAM Dendrimer Conjugates of Folic Acid and Methotrexate with Defined Ratio

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H. Zong K.-H. Lee, A. M. Desai, M.-H. Li, A. Kotlyar, Y. Zhang, P. R. Leroueil, J. J. Gam, M. M. Banaszak Holl, J. R. Baker .
Biomacromolecules
2012,
13,
982-991.
See:
Lee, Kyung-hoon

Biophysical Characterization of a Riboflavin-Conjugated Dendrimer Platform for Targeted Drug Delivery

Submitted by bhgroup_admin on Sat, 03/03/2012 - 16:32.

Biophysical Characterization of a Riboflavin-Conjugated Dendrimer Platform for Targeted Drug Delivery

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A. B. Witte, C. M. Timmer, J. J. Gam, S. K. Choi, M. M. Banaszak Holl, B. G. Orr, J. R. Baker, K. Sinniah.
Biomacromolecules
2012,
13,
507-516.
See:
Choi, Seok-ki

Effect of pH and Generation on Structural Properties of Poly(amidoamine) Dendrons Studied by Molecular Dynamics Simulations

Submitted by bhgroup_admin on Tue, 02/07/2012 - 00:22.

Effect of pH and Generation on Structural Properties of Poly(amidoamine) Dendrons Studied by Molecular Dynamics Simulations

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K.-H. Lee, I. Lee, J. R. Baker, M. M. Banaszak Holl.
Journal of Computational and Theoretical Nanoscience
2012,
9,
122-126.
See:
Lee, Kyung-hoon

Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting.

Submitted by bhgroup_admin on Fri, 01/20/2012 - 14:46.

Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting.

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M.H. Li, S. K. Choi, T. P. Thomas, A. Desai, K.-H. Lee, A. Kotlyar, M. M. Banaszak Holl, J. R. Baker.
European Journal of Medicinal Chemistry
2012,
47,
560-572.
See:
Lee, Kyung-hoon

Evaluation of a symmetry-based strategy for assembling protein complexes

Submitted by bhgroup_admin on Thu, 11/03/2011 - 13:18.

Evaluation of a symmetry-based strategy for assembling protein complexes

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D. P. Patterson, A. M. Desai, M. M. Banaszak Holl, E. N. G. Marsh.
RSC Advances
2011,
1,
1004-1012.
See:

Heterogeneous ligand-nanoparticle distributions: a major obstacle to scientific understanding and commercial translation

Submitted by bhgroup_admin on Wed, 08/17/2011 - 13:06.

Heterogeneous ligand-nanoparticle distributions: a major obstacle to scientific understanding and commercial translation

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D. G. Mullen, M. M. Banaszak Holl.
Accounts of Chemical Research
2011,
44,
1135-1252.
See:
Mullen, Douglas

Bioanalytical Screening of Riboflavin Antagonists for Targeted Drug Delivery

Submitted by bhgroup_admin on Thu, 06/09/2011 - 12:35.

Bioanalytical Screening of Riboflavin Antagonists for Targeted Drug Delivery-A Thermodynamic and Kinetic Study

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A. Plantinga, A Witte, M. H. Li, A. Harmon, S. K. Choi, M. M. Banaszak Holl, B. G. Orr, J. R. Baker, K. Sinniah.
ACS Medicinal Chemistry Letters
2011,
2,
363-367.
See:
Choi, Seok-ki

Design, Synthesis, and Biological Functionality of a Dendrimer-based Modular Drug Delivery Platform

Submitted by bhgroup_admin on Sun, 05/08/2011 - 01:58.
Design, Synthesis, and Biological Functionality of a Dendrimer-based Modular Drug Delivery Platform.
. D. Mullen, D. McNerny, A. Desai, X.-M. Chen, S. DiMaggio, A. Kotlyar, Y. Zhong, S. Qin, C. V. Kelly, T. Thomas, I. Majoros, B. G. Orr, J. R. Baker, M. M. Banaszak Holl.
Bioconjugate Chemistry
2011,
22,
679-689.
See:
DiMaggio, Stassi
Kelly, Christopher
McNerny, Dan
Mullen, Douglas

Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer ag

Submitted by bhgroup_admin on Sun, 05/08/2011 - 01:54.
Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent.
Y.-H. Zang, T. P. Thomas, K.-H. Lee, M. H. Li, H. Zong, A. M. Desai, A. Kotlyar, B. H. Hang, M. M. Banaszak Holl, J. R. Baker.
Bioorganic & Medicinal Letters
2011,
19,
2557-2564.
See:
Lee, Kyung-hoon

Acetonitrile Shortage: Use of isopropanol as an alternative elution system for ultrahigh performance liquid chromatograph

Submitted by bhgroup_admin on Sat, 04/02/2011 - 20:13.

Acetonitrile Shortage: Use of isopropanol as an alternative elution system for ultrahigh performance liquid chromatograph

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A. M. Desai, M. Andreae, D. G. Mullen, M. M. Banaszak Holl, J. R. Baker.
Analytical Methods
2011,
3,
56-58.
See:
Mullen, Douglas

Dual-wavelength linear regression phase unwrapping in three-dimensional microscopic images of cancer cells

Submitted by bhgroup_admin on Tue, 03/08/2011 - 23:52.

Dual-wavelength linear regression phase unwrapping in three-dimensional microscopic images of cancer cells

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A. Khmaladze, R. L. Matz, C. Zhang, T. Wang, M. M. Banaszak Holl, Z. Chen.
Optics Letters
2011,
36,
912-914.
See:
Matz, Becky
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